Drug NamePrazosin Drug UsesPrazosin is used for treating high blood pressure and benign prostatic hyperplasia (BPH). It may also be used for other conditions as determined by your doctor. How to useUse Prazosin as directed by your doctor.
- Take Prazosin by mouth with or without food.
Ask your health care provider any questions you may have about how to use Prazosin. Drug Class and MechanismPrazosin is in a class of drugs called alpha-adrenergic blockers. Prazosin causes the blood vessels (veins and arteries) to relax and expand, which allows blood to pass more easily through them. Missed DoseIf you miss a dose of Prazosin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Storage Store Prazosin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Prazosin out of the reach of children and away from pets. Possible Side EffectsCheck with your doctor if any of these most common side effects persist or become bothersome:
- constipation; depression; dizziness; drowsiness; dry mouth; feeling of a whirling motion; flushing; frequent urination; headache; lack of energy; lightheadedness; nasal congestion; nausea; nervousness; nosebleed; stuffy nose; swelling; vomiting; weakness.
Seek medical attention right away if any of these severe side effects occur:
- severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; fainting; pounding heartbeat; puffiness in hands or feet; rapid heartbeat.
More InformationPrazosin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor. Warnings/PrecautionsDo not use Prazosin if:
- you are allergic to any ingredient in Prazosin;
- you are taking modafinil.
Contact your doctor or health care provider right away if any of these apply to you.
Important :
- Prazosin may cause dizziness, lightheadedness, or fainting after the first dose. Take the first dose at bedtime. If you get up during the night, sit up and stand slowly. Continue to sit up and stand slowly while you are taking Prazosin.
- Avoid engaging in any hazardous tasks for at least 24 hours after taking the first dose, missing several doses, increasing the dose, or taking other high blood pressure medications.
- Before drinking alcohol, discuss it with your doctor.
- Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
- Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Prazosin while you are pregnant. Prazosin is found in breast milk. If you are or will be breast-feeding while you use Prazosin , check with your doctor. Discuss any possible risks to your baby.
What is prazosin?
Prazosin is in a class of drugs called alpha-adrenergic blockers. Prazosin causes the blood vessels (veins and arteries) to relax and expand, which allows blood to pass more easily through them.
Prazosin is used to treat hypertension (high blood pressure).
Prazosin may be used for purposes other than those listed in this medication guide.
What is the most important information I should know about prazosin?
To avoid falling, take the first dose at bedtime. Prazosin may cause dizziness. It is a good idea to take every dose at bedtime, if possible.
Use caution when you stand or sit up from a lying position, especially if you wake up during the night. Dizziness may occur when changing positions.
Do not stop taking this drug suddenly even if you feel better. Stopping suddenly could cause your blood pressure to increase.
Who should not take prazosin?
Before taking this medication, tell your doctor if you have any type of kidney or liver disease. You may need a dosage adjustment or special monitoring during therapy with prazosin. Prazosin is in the FDA pregnancy category C. This means that it is not known whether prazosin will harm an unborn baby. Do not take prazosin without first talking to your doctor if you are pregnant. Prazosin passes into breast milk and may affect a nursing baby. Do not take prazosin without first talking to your doctor if you are breast-feeding a baby.
How should I take prazosin?
Take prazosin exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water. To avoid falling, take the first dose at bedtime. Prazosin may cause dizziness. It is a good idea to take every dose at bedtime, if possible.
Use caution when you stand or sit up from a lying position, especially if you wake up during the night. Dizziness may occur when changing positions.
Do not stop taking this drug suddenly even if you feel better. Stopping suddenly could cause your blood pressure to increase. Store this medication at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication. A double dose could cause your blood pressure to become severely low.
If you miss doses for several days in a row, call your doctor before taking any additional doses. You may need to restart treatment with a lower dose.
What happens if I overdose?
Seek emergency medical attention.
Symptoms of a prazosin overdose include weakness, dizziness, and fainting; a weak, fast pulse; cold, clammy skin; and possibly loss of consciousness or coma.
What should I avoid while taking prazosin?
Avoid alcohol while taking prazosin. Alcohol may cause drowsiness or severely low blood pressure while taking prazosin. Use caution when driving, operating machinery, or performing other hazardous activities until you know how the medication affects you. Prazosin may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
Avoid becoming overheated. Low blood pressure, dizziness, and fainting could result. Be careful not to overexert yourself, and use caution in hot weather.
Prazosin side effects
If you experience any of the following serious side effects, stop taking prazosin and seek emergency medical attention or contact your doctor immediately:
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an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
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an increased heartbeat;
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shortness of breath or chest pain; or
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a rash.
Other, less serious side effects may be more likely to occur. Continue to take prazosin and talk to your doctor if you experience
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vivid dreams;
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dizziness or drowsiness;
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weakness, fatigue, or ill feeling;
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nausea, vomiting, diarrhea, constipation, abdominal pain, or decreased appetite;
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fluid retention or slight weight gain;
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joint or muscle aches;
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headache, irritability, or depression;
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increased urination;
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decreased sex drive; or
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numbness or tingling in your hands, feet, arms, or legs.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Prazosin Dosing Information
Usual Adult Dose for Congestive Heart Failure: Initial dose: 1 mg orally 2-3 times a day.
Maintenance dose: 6-15 mg daily given in divided doses. Usual Adult Dose for Hypertension: Initial dose: 1 mg orally 2-3 times a day.
Maintenance dose: 6-15 mg daily given in divided doses. Usual Adult Dose for Benign Prostatic Hyperplasia: Initial dose: 1 mg orally 2-3 times a day.
Maintenance dose: 6-15 mg daily given in divided doses. Usual Pediatric Dose for not applicable: Greater than 1 year:
Initial dose: 5 mcg/kg orally.
Maintenance dose: Increase dose gradually up to 25 mcg/kg orally every 6 hours. Maximum daily dose is 15 mg or 0.4 mg/kg/day.
What other drugs will affect prazosin?
Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal supplements, during treatment with prazosin.
Where can I get more information?
- Your pharmacist has additional information about prazosin written for health professionals that you may read
What does my medication look like?
Prazosin is available with a prescription under the brand name Minipress. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.
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Minipress 1 mg--white capsules
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Minipress 2 mg--pink/white capsules
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Minipress 5 mg--blue/white capsules
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