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There is a number of reasons for that. We do not spend anything on marketing, there are no taxes to be paid as the product comes into the country unregistered, the manufacturer is located in an offshore zone and the production costs are way lower. No child labor is used.
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Blood Pressure/Cholesterol

Lozol
Lozol (Indapamide)
Lozol (Indapamide) is used to treat hypertension (high blood pressure).
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Drug Name

Lozol (Indapamide)


Drug Uses

Lozol is used to treat hypertension (high blood pressure). It also is used to eliminate fluid when the body accumulates excess fluid, such as with edema and congestive heart failure.


How to use

Lozol is taken as a single daily dose, generally in the morning before breakfast. It can be taken with or without food. Antacids have no effect on the activity of Lozol.


Drug Class and Mechanism

Lozol is a diuretic (water pill) that is primarily used for the treatment of high blood pressure. It works by preventing the kidney from reabsorbing (retaining in the body) salt and water that is destined to be eliminated in the urine. This results in increased urine output (diuresis). Lozol also is thought to reduce the salt in the smooth muscle of the walls of blood vessels. (The salt ultimately is eliminated in the urine.) The loss of salt from the muscle causes the muscle to relax, and the relaxation of the vessels results in reduced blood pressure.


Missed Dose

If you miss a dose of Propecia and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to you regular dosing schedule. Do not take 2 doses at once.


Storage

Lozol should be stored between 15 degrees C (59 degrees F) and 30 degrees C (86 degrees F).


Possible Side Effects

Dehydration may occur during lozol therapy. Hypokalemia (low blood potassium due to elimination of potassium in the urine) is one of the most common adverse effects associated with the thiazide class of diuretics and may cause abnormal cardiac rhythms. The most common symptom associated with hypokalemia is muscle weakness. Patients receiving lozol may need potassium supplements to prevent hypokalemia. Hypomagnesemia (low blood magnesium) also may occur. Other possible side effects include excessive loss of sodium (particularly of concern in elderly patients), increased cholesterol (this effect tends to diminish with continued use), increased uric acid concentrations in the blood, dizziness, lightheadedness, headache, blurred vision, tingling of the extremities, nervousness, impotence, rash, photosensitivity (skin rashes due to sunlight), fatigue, irritability, and agitation.



More Information

If you have any questions about Casodex, please talk with your doctor, pharmacist, or other health care provider.

Casodex is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.


Warnings/Precautions

If you have had a severe allergic reaction to this medicine or to any other sulfonamide medicine (such as Septra DS, Bactrim DS, Gantrisin, glyburide, or probenecid), contact your doctor before taking this medicine. A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. If you have a question about whether you are allergic to this medicine or if a certain medicine is a sulfonamide, contact your doctor or pharmacist. Your doctor may have also prescribed a potassium supplement for you. If so, follow the dosing carefully. Do not start taking additional potassium on your own or change your diet to include more potassium without first checking with your doctor. This medicine may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. For women: it is unknown if this medicine is excreted in breast milk. Do not breast-feed while taking this medicine.


What is Lozol (indapamide)?

Indapamide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Indapamide treats fluid retention (edema) in people with congestive heart failure. This medication is also used to treat high blood pressure (hypertension).

Indapamide may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Lozol (indapamide)?

Do not use this medication if you have severe kidney disease or are unable to urinate, if you have severe liver disease, or if you have low potassium levels in your blood (hypokalemia).

Before using this medication, tell your doctor if you have liver disease, kidney disease, gout, lupus, diabetes, or an allergy to sulfa drugs.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

What should I discuss with my doctor before taking Lozol (indapamide)?

Do not use this medication if you have:
  • severe kidney disease or are unable to urinate;
  • severe liver disease; or
  • low potassium levels in your blood (hypokalemia).

Before using indapamide, tell your doctor if you have:

  • kidney disease;
  • liver disease;
  • gout;

  • lupus;

  • diabetes; or

  • an allergy to sulfa drugs.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take indapamide.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether indapamide passes into breast milk or if it could cause harm to a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Lozol (indapamide)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. Do not miss any scheduled appointments.

Your blood and urine may both be tested if you have been vomiting or are dehydrated.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Store the tablets at room temperature away from heat, light, and moisture.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms of a indapamide overdose may include nausea, weakness, dizziness, dry mouth, thirst, and muscle pain or weakness.

What should I avoid while taking Lozol (indapamide)?

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Lozol (indapamide) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:
  • dry mouth, thirst, nausea, vomiting;

  • feeling weak, drowsy, restless, or light-headed;

  • fast or uneven heartbeat; or

  • muscle pain or weakness.

Less serious side effects may include:

  • dizziness;

  • headache; or

  • mild skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect Lozol (indapamide)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

  • lithium;

  • baclofen (Lioresal);

  • other blood pressure medications;

  • steroids (prednisone and others);

  • insulin or diabetes medicine taken by mouth;

  • salicylates such as aspirin, Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others;

  • an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), ramipril (Altace), and others;

  • NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen (Motrin, Advil), diclofenac (Voltaren), indomethacin, naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others; or

  • amiodarone (Cordarone, Pacerone), bepridil (Vascor), chloroquine (Arelan), cisapride (Propulsid), clarithromycin (Biaxin), disopyramide (Norpace), dofetilide (Tikosyn), droperidol (Inapsine), erythromycin (Erythrocin, E.E.S), haloperidol (Haldol), pentamidine (NebuPent, Pentam), pimozide (Orap), procainamide (Procan), quinidine (Cardioquin, Quinaglute), sotalol (Betapace), sparfloxacin (Zagam), or thioridazine (Mellaril).

This list is not complete and there may be other drugs that can interact with indapamide. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about indapamide.
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