Drug NameLasix (Furosemide) Drug UsesFurosemide is a powerful diuretic. Furosemide is used to treat excessive fluid accumulation and swelling (edema) of the body caused by heart failure, cirrhosis, chronic kidney failure, and nephrotic syndrome. It is sometimes used in conjunction with other blood pressure pills to treat high blood pressure. How to useTake furosemide exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. To reduce nighttime urination, take furosemide early in the day unless otherwise directed by your doctor. It is important to take furosemide regularly to get the most benefit. Do not stop taking furosemide suddenly even if you feel better. Stopping suddenly could make your condition worse. Drug Class and MechanismFurosemide is a potent diuretic (water pill). Furosemide works by blocking the absorption of salt and fluid in the kidney tubules, causing a profound increase in urine output (diuresis). The diuretic effect of furosemide can cause body water and electrolyte depletion. Therefore, careful medical supervision is necessary during treatment. Missed DoseIf you take one dose daily, take the missed dose as soon as you remember within 12 hours. If more than 12 hours have passed, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication.
If you take more than one dose daily, take the missed dose up to 2 hours late. If more than 2 hours have passed, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication. Storage Should be stored at room temperature in a light resistant container. Possible Side EffectsCommonly observed side effects are low blood pressure, and water and electrolyte depletion. Less common side effects include jaundice, ringing in ears (tinnitus), light sensitivity, rash, pancreatitis, nausea, abdominal pain, dizziness, anemia, and other blood disorders. More Information
- If you experience any of the following serious side effects, stop taking furosemide and seek emergency medical attention or call your doctor immediately:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- muscle cramps or weakness;
- an irregular heartbeat;
- abdominal pain or diarrhea;
- low blood pressure (weakness, dizziness, fatigue); or
- decreased hearing.
- Other, less serious side effects may be more likely to occur. Continue to take furosemide and talk to your doctor if you experience
- dry mouth or increased thirst;
- headache, dizziness, or lightheadedness;
- constipation;
- increased sensitivity to sunlight;
- a rash;
- jaundice (yellow skin or eyes);
- ringing in the ears;
- nausea;
- easy bleeding or bruising; or
- numbness in the hands or feet.
- Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Warnings/PrecautionsPatients allergic to sulfa may also be allergic to furosemide because of a similarity in the chemical structure of the medications. Furosemide should be avoided in kidney failure. Even though furosemide is important in treating excess fluid accumulation in patients with cirrhosis, sudden loss of fluid and electrolytes in these patients can worsen kidney function and even cause the patient to go into a coma. Furosemide can cause lowering of blood potassium, sodium, and magnesium levels. Low potassium and magnesium levels can lead to heart rhythm abnormalities, especially in patients already taking digoxin (Lanoxin). Please visit the digoxin (Lanoxin) site for further information.
Blood uric acid levels can increase during furosemide treatment, but precipitation of acute gout is rare. Furosemide may increase the toxic effect of aminoglycoside antibiotics on the ear, especially in patients with kidney dysfunction. Furosemide reduces the kidney excretion of lithium and can lead to lithium toxicity. Furosemide may impair kidney function when administered together with aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Periodic blood tests are performed to monitor kidney function and electrolytes during treatment with furosemide.
What is furosemide?
Furosemide is a loop diuretic (water pill) that prevents your body from absorbing too much salt, allowing the salt to instead be passed in your urine.
Furosemide treats fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome. This medication is also used to treat high blood pressure (hypertension).
Furosemide may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about furosemide?
Do not use this medication if you are unable to urinate.
Before using this medication, tell your doctor if you have kidney disease, liver disease, gout, lupus, diabetes, or an allergy to sulfa drugs.
To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled appointments.
Furosemide will make you urinate more often and you may get dehydrated easily. Follow your doctor's instructions about using potassium supplements or getting enough salt and potassium in your diet.
Avoid becoming dehydrated. Follow your doctor's instructions about the type and amount of liquids you should drink while you are taking furosemide.
If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.
What should I discuss with my healthcare provider before taking furosemide?
Do not use this medication if you are unable to urinate.
Before using furosemide, tell your doctor if you have:
If you have any of these conditions, you may need a dose adjustment or special tests to safely take furosemide.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Furosemide can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take furosemide?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Furosemide will make you urinate more often and you may get dehydrated easily. Follow your doctor's instructions about using potassium supplements or getting enough salt and potassium in your diet.
To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled appointments.
If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.
Store this medication at room temperature away from heat, light, and moisture.
What happens if I miss a dose?
Furosemide is sometimes used only once, so you may not be on a dosing schedule. If you are using the medication regularly, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include ringing in your ears, loss of appetite, weakness, dizziness, confusion, feeling light-headed, or fainting.
What should I avoid while taking furosemide?
Avoid becoming dehydrated. Follow your doctor's instructions about the type and amount of liquids you should drink while you are taking furosemide.
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Furosemide can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
What are the possible side effects of furosemide
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using furosemide and call your doctor at once if you have any of these serious side effects:
-
dry mouth, thirst, nausea, vomiting;
-
feeling weak, drowsy, restless, or light-headed;
-
fast or uneven heartbeat;
-
muscle pain or weakness;
-
urinating less than usual or not at all;
-
easy bruising or bleeding, unusual weakness;
-
a red, blistering, peeling skin rash;
-
hearing loss; or
-
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
-
diarrhea, constipation, or stomach pain;
-
headache;
-
numbness, burning, pain, or tingly feeling;
-
dizziness; or
-
blurred vision.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect furosemide?
If you take sucralfate (Carafate), take it at least 2 hours before or after you take furosemide.
Before taking this medication, tell your doctor if you are using any of the following drugs:
-
lithium;
-
digoxin (Lanoxin);
-
steroids (prednisone and others);
-
ethacrynic acid (Edecrin);
-
diet pills or cold medicine;
-
other blood pressure medications;
-
amikacin (Amikin), gentamicin (Garamycin), netilmicin (Netromycin), streptomycin, tobramycin (Nebcin, Tobi);
-
salicylates such as aspirin, Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others; or
-
indomethacin.
This list is not complete and there may be other drugs that can interact with furosemide. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about furosemide.
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