Drug NameLanoxin (Digoxin) Drug UsesLanoxin is used for treating heart failure and slowing the heart rate in patients with chronic atrial fibrillation, a type of abnormal heart rhythm. It may also be used for certain conditions as determined by your doctor. How to useUse Lanoxin as directed by your doctor.
- Lanoxin may be taken with or without food.
- Using Lanoxin at the same time each day will help you to remember.
Ask your health care provider any questions you may have about how to use Lanoxin. Drug Class and MechanismLanoxin is a digitalis glycoside. It works by increasing the force of contraction of the heart and slowing heart rate. Missed DoseIf you miss a dose of Lanoxin , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Storage Store at the room temperature away from moisture and sunlight. Keep out of the reach of children. Possible Side EffectsCheck with your doctor if any of these most common side effects persist or become bothersome:
- diarrhea; fast, slow, or irregular heartbeat; loss of appetite; nausea; vomiting; weakness.
Seek medical attention right away if any of these severe side effects occur:
- severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); heart disturbances.
More InformationLanoxin is to be used only by the patient for whom it is prescribed. Do not share it with other people. Warnings/PrecautionsDo not use Lanoxin if:
- you are allergic to any ingredient in Lanoxin or other digitalis medicines;
- you have Beriberi heart disease;
- you have certain types of heart rhythm problems, such as ventricular fibrillation.
Contact your doctor or health care provider right away if any of these apply to you.
Important:
- Tell your doctor or dentist that you take Lanoxin before you receive any medical or dental care, emergency care, or surgery.
- Lab tests, including electrocardiogram (ECG), electrolytes, and blood digoxin levels, may be performed while you use Lanoxin . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Lanoxin with caution in the elderly; they may be more sensitive to its effects.
- Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lanoxin while you are pregnant. Lanoxin is found in breast milk. If you are or will be breast-feeding while you use Lanoxin, check with your doctor. Discuss any possible risks to your baby.
What is digoxin?
Digoxin is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm.
Digoxin is used to treat congestive heart failure.
Digoxin is also used to treat atrial fibrillation, a heart rhythm disorder of the atria (the upper chambers of the heart that allow blood to flow into the heart).
Digoxin may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about digoxin?
You should not use this medication if you are allergic to digoxin, or if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).
Before using digoxin, tell your doctor if you have certain heart conditions, especially "AV block" (unless you have a pacemaker), or a recent history of heart attack. Also tell your doctor if you have kidney disease, a thyroid disorder, an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood), or if you are malnourished or have recently been sick with vomiting or diarrhea.
Keep taking digoxin as directed, even if you feel well. Get your prescription refilled before you run out of medicine completely.
Do not stop taking digoxin without first talking to your doctor. Stopping suddenly may make your condition worse.
Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Digoxin overdose can occur more easily if you are dehydrated.
There are many other medicines that can interact with digoxin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
What should I discuss with my healthcare provider before taking digoxin?
You should not use this medication if you are allergic to digoxin, or if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before using digoxin, tell your doctor if you have:
-
certain heart conditions, especially "AV block" (unless you have a pacemaker);
-
a recent history of heart attack;
- kidney disease;
-
a thyroid disorder;
-
an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood); or
-
if you are malnourished or have recently been sick with vomiting or diarrhea.
FDA pregnancy category C. Digoxin may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Digoxin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from digoxin.
How should I take digoxin?
Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
Take digoxin with a full glass of water.
Try to take the medication at the same time every day.
Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
To be sure this medication is not causing harmful effects, your blood may need to be tested on a regular basis. Your kidney function may also need to be tested. Do not miss any scheduled appointments.
Keep taking digoxin as directed, even if you feel well. Get your prescription refilled before you run out of medicine completely.
Do not stop taking digoxin without first talking to your doctor. Stopping suddenly may make your condition worse. Store this medication at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If your next dose is less than 12 hours away, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include nausea, vomiting, diarrhea, loss of appetite, blurred vision, seeing halos around lights or objects, severe skin rash, fast/slow or uneven heartbeats, and feeling like you might pass out.
What should I avoid while taking digoxin?
Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Digoxin overdose can occur more easily if you are dehydrated.
Digoxin side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:
-
fast, slow, or uneven heart rate;
-
bloody or black, tarry stools;
-
blurred vision, yellowed vision; or
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confusion, hallucinations, unusual thoughts or behavior.
Less serious side effects may include:
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mild nausea, vomiting, diarrhea;
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feeling weak or dizzy;
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headache;
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enlarged breasts in men; or
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mild skin rash.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect digoxin?
Many drugs can interact with digoxin. Below is just a partial list. Tell your doctor if you are using:
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an antacid, or Kaopectate;
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alprazolam (Xanax);
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cancer medications;
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clonidine (Catapres);
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supplements or medications that contain calcium;
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a diuretic (water pill), such as spironolactone (Aldactone, Aldactazide);
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amphotericin B (Fungizone, AmBisome, Abelcet);
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cholestyramine (Questran, Prevalite);
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epinephrine (EpiPen);
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guanabenz (Wytensin) or guanfacine (Tenex);
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indomethacin (Indocin);
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isoproterenol (Isuprel);
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itraconazole (Sporanox);
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levothyroxine (Synthroid, Levothroid, and others);
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methyldopa (Aldomet);
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metoclopramide (Reglan);
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neomycin (Mycifradin, Neo-Fradin, Neo-Tab);
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rifampin (Rifadin, Rifater, Rifamate);
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sulfasalazine (Azulfidine); or
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an antibiotic such as erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), clarithromycin (Biaxin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap);
-
a beta-blocker such as carvedilol (Coreg), metoprolol (Lopressor, Toprol), and others;
-
a calcium channel blocker such as amlodipine (Norvasc), diltiazem (Tiazac, Cartia, Cardizem), felodipine (Plendil), nisoldipine (Sular), verapamil (Calan, Covera, Isoptin, Verelan), and others;
-
decongestant cold or allergy medicine, or nasal sprays such as Afrin, Duramist, Neo-Synephrine, Tysine Nasal, and others;
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a heart rhythm medication such as amiodarone (Cordarone, Pacerone), propafenone (Rythmol), or quinidine (Quinaglute, Quinidex, Quin-Release); or
-
steroids such as prednisone, fluticasone (Advair), mometasone (Asmanex, Nasonex), dexamethasone (Decadron, Hexadrol) and others.
This list is not complete and there are many other medicines that can interact with digoxin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
Where can I get more information?
- Your pharmacist can provide more information about digoxin.
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