Drug NameInderal (Propranolol) Drug UsesInderal is for treating high blood pressure; prevention of angina pectoris (chest pain); management of a heart condition called hypertrophic subaortic stenosis; treating and preventing certain abnormal or rapid heart rhythms; improvement of survival after a heart attack in certain patients; treatment of tremor; prevention of migraine headaches; and treating symptoms of adrenal gland tumors. How to useUse Inderal as directed by your doctor.
- Take Inderal by mouth with or without food, but it should be taken at the same time daily and consistently either on an empty stomach or with food;
- Do not take antacids containing aluminum within 2 hours of taking Inderal;
- Continue to use Inderal even if you feel well. Do not miss any doses.
Ask your health care provider any questions you may have about how to use Inderal. Drug Class and MechanismInderal is a beta-adrenergic blocking agent. It works by slowing down the heart and reducing blood pressure, which helps it pump more efficiently and reduces the workload on the heart. Missed DoseIf a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your doctor. If more than one dose is missed, contact your doctor or pharmacist. Storage Store Inderal between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Inderal out of the reach of children and away from pets. Possible Side EffectsCheck with your doctor if any of these most common side effects persist or become bothersome:
- constipation; depression; diarrhea; dizziness; drowsiness; fatigue; hallucinations; lightheadedness; nausea; sleeplessness; stomach cramps; tiredness; vision problems; vivid dreams; vomiting; weakness.
Seek medical attention right away if any of these severe side effects occur:
- severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).
More InformationInderal is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If you have any questions about Inderal , please talk with your doctor, pharmacist, or other health care provider. Warnings/PrecautionsDo not use Inderal if:
- you are allergic to any ingredient in Inderal;
- you have a very slow heartbeat and heart block; had a heart attack and have very low blood pressure or uncontrolled heart failure or shock caused by heart failure;
- you have asthma or Raynaud phenomenon ;
- you are a child with diabetes or heart failure;
- you are taking mibefradil.
Contact your doctor or health care provider right away if any of these apply to you.
Important :
- Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Check with your doctor before drinking alcohol while you are taking Inderal.
- Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel normal. Tell your doctor if you develop any new symptoms.
- Inderal may mask the signs of hyperthyroidism (overactive thyroid). If you have an overactive thyroid and stop taking Inderal too suddenly, symptoms of hyperthyroidism (eg, fast heartbeat) may occur.
- Patients with a history of severe allergic reactions may be more sensitive to allergens while taking Inderal . These patients may not respond to the usual dose of epinephrine (adrenalin).
- Diabetes patients - Inderal may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you hungrier. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Tell your doctor or dentist that you take Inderal before you receive any medical or dental care, emergency care, or surgery.
- Inderal may interfere with certain lab tests, including the glaucoma screening test. Be sure your doctor and lab personnel know you are taking Inderal.
- Lab tests, including blood pressure and heart function tests, may be performed while you use Inderal . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Inderal while you are pregnant. Inderal is found in breast milk. If you are or will be breast-feeding while you use Inderal , check with your doctor. Discuss any possible risks to your baby.
What is propranolol?
Propranolol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).
Propranolol is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions. It is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches.
Propranolol may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about propranolol?
You should not use this medication if you are allergic to propranolol, or if you have asthma or certain heart conditions, especially second or third degree heart block. Do not stop taking propranolol without first talking to your doctor. Stopping suddenly may make your condition worse.
If you need to have any type of surgery, you may need to temporarily stop using propranolol. Be sure the surgeon knows ahead of time that you are using propranolol.
Avoid drinking alcohol. It may increase your blood levels of propranolol.
Propranolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.
Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.
What should I discuss with my healthcare provider before taking propranolol?
You should not use this medication if you are allergic to propranolol, or if you have asthma or certain heart conditions, especially second or third degree heart block.
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking propranolol, tell your doctor if you have:
-
bronchitis, emphysema, or other breathing disorders;
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diabetes;
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low blood pressure;
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a heart problem such as heart block, sick sinus syndrome, slow heart rate, or congestive heart failure;
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depression;
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liver or kidney disease;
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a thyroid disorder;
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pheochromocytoma; or
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problems with circulation (such as Raynaud's syndrome).
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Propranolol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take propranolol?
Take propranolol exactly as it was prescribed for you. Do not take the medication in larger amounts or for longer than recommended by your doctor. Follow the directions on your prescription label.
Take this medication with a full glass of water.
Take propranolol at the same time every day.
Do not crush, chew, break, or open an extended-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.
To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Do not skip doses or stop taking propranolol without first talking to your doctor. Stopping suddenly may make your condition worse.
To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.
If you need to have any type of surgery, tell the surgeon that you are using propranolol. You may need to briefly stop using propranolol before having surgery.
Propranolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.
Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.
Store propranolol at room temperature away from moisture and heat.
What happens if I miss a dose?
For regular (short-acting) propranolol: Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the missed dose and take the medicine at the next regularly scheduled time.
For extended-release propranolol (Inderal LA, InnoPran XL and others): Take the missed dose as soon as you remember. If your next dose is less than 8 hours away, skip the missed dose and take the medicine at the next regularly scheduled time.
Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include slow or uneven heartbeats, dizziness, weakness, or fainting.
What should I avoid while taking propranolol?
Avoid drinking alcohol. It may increase your blood levels of propranolol.
Propranolol side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
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fast, slow, or uneven heartbeats;
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feeling light-headed, fainting;
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feeling short of breath, even with mild exertion;
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swelling of your ankles or feet;
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fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
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nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
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depression, confusion, hallucinations; or
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cold feeling in your hands and feet.
Less serious side effects may include:
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nausea, vomiting, diarrhea, constipation, stomach cramps;
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decreased sex drive, impotence, or difficulty having an orgasm;
-
sleep problems (insomnia); or
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tired feeling.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect propranolol?
Tell your doctor about all other medications you use, especially:
-
clonidine (Catapres);
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digitalis (digoxin, Lanoxin);
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dobutamine (Dobutrex);
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haloperidol (Haldol);
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isoproterenol (Isuprel);
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a blood thinner such as warfarin (Coumadin);
-
an antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Janimine, Tofranil), and others;
-
an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate);
-
aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), and others;
-
doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin);
-
a heart medication such as nifedipine (Procardia, Adalat), reserpine (Serpasil), diltiazem (Cartia, Cardizem), or verapamil (Calan, Verelan, Isoptin);
-
amiodarone (Cordarone, Pacerone), propafenone (Rythmol), quinidine (Quinaglute, Quinidex, Quin-Release); or
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an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).
This list is not complete and there may be other drugs that can interact with propranolol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist can provide more information about propranolol.
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