Drug NameCapoten (Captopril) Drug UsesCapoten can be used alone in treating high blood pressure. Its blood pressure lowering effect can be further enhanced by the addition of a diuretic (water pill) medication. Capozide is an example of a medication that combines the effect of capoten with a diuretic (water pill). By reducing resistance in the arteries, capoten can be useful in the treatment of congestive heart failure. In treating heart failure, capoten usually supplements conventional treatment, including a diuretic and digoxin (Lanoxin). After a heart attack, capoten has been found to be effective in improving functioning of the damaged heart. It is also used to treat kidney disease associated with diabetes. How to useCapoten should be taken on an empty stomach one hour before meals. Do not take antacids containing aluminium or magnesium within 1 hour before or 2 hours after taking this medicine. Drug Class and MechanismCapoten is an ACE (angiotensin converting enzyme) inhibitor. ACE is an enzyme in the body which is important for the formation of angiotensin II. Angiotensin II causes constriction of arteries in the body, thereby elevating blood pressure. ACE inhibitors such as captopril lower blood pressure by inhibiting the formation of angiotensin II, thus relaxing the arteries. Relaxing the arteries not only lowers blood pressure, but also improves the pumping efficiency of a failing heart and improves cardiac output in patients with heart failure. Missed DoseIf you miss a dose of Geodon , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once. Storage Store this medicine at room temperature, away from heat, moisture, and light. Possible Side EffectsSide effects that may occur while taking this medicine include cough, dizziness or lightheadedness, drowsiness, and taste changes. If they continue or are bothersome, check with your doctor. Check with your doctor as soon as possible if you experience severe lightheadedness or fainting; fast or irregular heartbeat; prolonged nausea, vomiting, or diarrhea; a change in the amount of your urine; unusual joint pain; or unusual muscle pain, cramps, or weakness. Contact your doctor immediately if you experience swelling of hands, legs, face, lips, eyes, throat, tongue, or trunk; difficulty swallowing or breathing; hoarseness; chest pain; unusual stomach pain; yellowing of the skin or eyes; darkening of your urine; sore throat; or fever. An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. More InformationDo not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions.
If you will be taking this medicine for an extended period of time, be sure to obtain necessary refills before your supply runs out. Warnings/PrecautionsDo not take this medicine if you have had an allergic reaction to it, other ACE inhibitors, or if you are allergic to any ingredient in this product. Do not exceed the recommended dose without checking with your doctor. It may take several weeks for this medicine to work. Do not stop using this medicine without checking with your doctor. Laboratory and/or medical tests including liver function, kidney function, blood pressure, blood counts, and blood electrolytes may be performed to monitor your progress or to check for side effects. Keep all doctor and laboratory appointments while you are taking this medicine. This medicine may affect certain lab test results. Make sure laboratory personnel and your doctors know you use this medicine. Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using this medicine. This medicine may cause dizziness, lightheadedness, or fainting, especially when you begin taking this medicine. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. If dizziness occurs, sit up or stand slowly.
This medicine may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to this medicine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. Drink plenty of fluids during exercise or other activities where excessive sweating may occur. If you experience difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more of this medicine unless your doctor tells you to do so. This medicine may lower your resistance to infection. Prevent infection by avoiding contact with people with colds or other infections.
Do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first.
Do not use a salt substitute or other potassium supplement without checking with your doctor. Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. Caution is advised when using this medicine in the elderly or in children because they may be more sensitive to the effects of the medicine.
For women: use of this medicine during pregnancy has resulted in fetal and newborn death. If you think you may be pregnant, contact your doctor immediately. This medicine is excreted in breast milk. Do not breast-feed while taking this medicine.
What is captopril?
Captopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.
Captopril is used to treat high blood pressure (hypertension), congestive heart failure, kidney problems caused by diabetes, and to improve survival after a heart attack.
Captopril may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about captopril?
Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Captopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of captopril. Do not use salt substitutes or potassium supplements while taking captopril, unless your doctor has told you to.
Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking captopril. Drink plenty of water each day while you are taking this medication.
What should I discuss with my healthcare provider before taking captopril?
Do not use this medication if you are allergic to captopril or to any other ACE inhibitor, such as benazopril (Lotensin), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).
Before using captopril, tell your doctor if you are allergic to any drugs, or if you have:
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kidney disease (or if you are on dialysis);
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liver disease;
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heart disease or congestive heart failure;
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diabetes; or
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a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.
If you have any of these conditions, you may not be able to use captopril, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Captopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Captopril can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take captopril?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Take each dose with a full glass of water.
Captopril is usually taken 1 hour before meals. Follow your doctor's instructions.
Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking captopril. Drink plenty of water each day while you are taking this medication.
To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
If you need to have any type of surgery, tell the surgeon ahead of time that you are taking captopril. You may need to stop using the medicine for a short time.
If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.
Store captopril at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a captopril overdose may include feeling extremely dizzy or light-headed, or fainting.
What should I avoid while taking captopril?
Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of captopril. Do not use salt substitutes or potassium supplements while taking captopril, unless your doctor has told you to.
Captopril side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
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feeling light-headed, fainting;
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urinating more or less than usual, or not at all;
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fever, chills, body aches, flu symptoms;
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pale skin, easy bruising or bleeding;
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fast, pounding, or uneven heartbeats;
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chest pain; or
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swelling, rapid weight gain.
Less serious side effects may be more likely to occur, such as:
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cough;
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loss of taste sensation, loss of appetite;
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dizziness, drowsiness, headache;
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sleep problems (insomnia);
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dry mouth, sores in the mouth or on the lips;
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nausea, diarrhea, constipation; or
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mild skin itching or rash.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect captopril?
Before taking captopril, tell your doctor if you are taking any of the following drugs:
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lithium (Lithobid, Eskalith);
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a potassium supplement such as K-Dur, Klor-Con;
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salt substitutes that contain potassium;
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drugs that can dilate blood vessels, such as alprostadil (Caverject, Edex), nitroglycerin, nitroprusside (Nitropress), nesiritide (Natrecor), minoxidil (Loniten), or isosorbide dinitrate (Imdur, Isordil);
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aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others; or
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a diuretic (water pill).
If you are using any of these drugs, you may not be able to use captopril or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect captopril. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist has information about captopril written for health professionals that you may read.
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