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Blood Pressure/Cholesterol

Adalat
Adalat (Nifedipine)
Adalat (Nifedipine) is used to lower hypertension and to treat chest pain.
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Drug Name

Adalat (Nifedipine)


Drug Uses

Adalat is is used to lower hypertension (high blood pressure) and to treat angina (chest pain).


How to use

Use Adalat as directed by your doctor.

  • Take Adalat by mouth. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.
  • Swallow Adalat whole. Do not break, crush, or chew before swallowing.
Ask your health care provider any questions you may have about how to use Adalat.


Drug Class and Mechanism

Adalat works by interfering with the normal action of calcium in blood vessel constriction (relaxes the blood vessels) and heart muscle contraction (heart may beat with less force and pump out less blood) and nerve conduction in the heart (heart may beat more slowly and more regularly).


Missed Dose

If you miss a dose of Adalat, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.


Storage

Store at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep out of the reach of children and away from pets.


Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

  • constipation; dizziness; flushing; giddiness; headache; heat sensation; heartburn; lightheadedness; nausea; weakness.
Seek medical attention right away if any of these severe side effects occur:

  • severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); irregular pulse; shortness of breath; swelling of the feet or hands; tender, bleeding, or swollen gums.



More Information

Adalat is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If you have any questions about Adalat, please talk with your doctor, pharmacist, or other health care provider.


Warnings/Precautions

Do not use Adalat if:

  • you are allergic to any ingredient in Adalat.
Contact your doctor or health care provider right away if any of these apply to you.

Important :
  • Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Proper dental care is important while you are taking Adalat. Brush and floss your teeth and visit the dentist regularly.
  • Use Adalat with caution in the elderly; they may be more sensitive to its effects.
  • If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Adalat while you are pregnant. It is not known if Adalat is found in breast milk. If you are or will be breast-feeding while you use Adalat, check with your doctor. Discuss any possible risks to your baby.


What is Adalat CC (nifedipine)?

Nifedipine is in a class of drugs called calcium channel blockers. Nifedipine relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Nifedipine is used to lower hypertension (high blood pressure) and to treat angina (chest pain).

Nifedipine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Adalat CC (nifedipine)?

Do not stop taking nifedipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse. Do not crush, chew, or break any form of nifedipine. Swallow the pills whole. Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You should discuss the use of grapefruit and grapefruit juice with your doctor.

What should I discuss with my healthcare provider before taking Adalat CC (nifedipine)?

Before taking nifedipine, tell your doctor if you have

  • kidney disease;
  • liver disease;

  • another disease of the heart or blood vessels such as sick sinus syndrome, aortic stenosis, heart failure, low blood pressure, or coronary artery disease.

You may not be able to take nifedipine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Nifedipine is in the FDA pregnancy category C. This means that it is not known whether nifedipine will be harmful to an unborn baby. Do not take nifedipine without first talking to your doctor if you are pregnant or could become pregnant during treatment. Nifedipine passes into breast milk. Do not take nifedipine without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from nifedipine. Your doctor may prescribe a lower dose of this medication.

How should I take Adalat CC (nifedipine)?

Take nifedipine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Adalat CC should be taken on an empty stomach. Do not crush, chew, or break any form of nifedipine. Swallow the pills whole. Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You should discuss the use of grapefruit and grapefruit juice with your doctor.

Occasionally, the Procardia XL tablet shell may be seen in the stool. This is not harmful. The medicine has been absorbed by the body and the tablet shell is designed to be eliminated in the stool.

Do not stop taking nifedipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse. Store nifedipine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a nifedipine overdose include dizziness, weakness, chest pain, shortness of breath, fainting, an unusually fast or slow heartbeat, coma, slurred speech, and confusion.

What should I avoid while taking Adalat CC (nifedipine)?

Do not consume grapefruit or grapefruit juice during treatment with nifedipine. Nifedipine can interact with grapefruit and grapefruit juice, and the interaction may have dangerous effects. You should discuss the use of grapefruit and grapefruit juice with your doctor.

Follow any recommendations your doctor makes about diet or exercise.

Use caution when you stand or sit up from a lying position, especially if you wake up during the night. You may become dizzy when changing positions. Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness or dizziness while taking nifedipine.

Adalat CC (nifedipine) side effects

If you experience any of the following serious side effects, stop taking nifedipine and contact your doctor immediately or seek emergency medical treatment:
  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

  • unusually fast or slow heartbeats;

  • severe dizziness or fainting;

  • psychosis;

  • yellowing of the skin or eyes (jaundice); or

  • swelling of the legs or ankles.

Other, less serious side effects may be more likely to occur. Continue to take nifedipine and talk to your doctor if you experience

  • headache, fatigue, or tiredness;

  • flushing;

  • insomnia;

  • vivid or abnormal dreams;

  • nausea or constipation; or

  • increased urination.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Adalat CC (nifedipine)?

Before taking nifedipine, tell your doctor if you are taking any of the following drugs:

  • another heart medication to treat the same or another condition;

  • cimetidine (Tagamet, Tagamet HB);

  • erythromycin (E-Mycin, E.E.S., Eryc, Ery-Tab, others);

  • itraconazole (Sporanox) or ketoconazole (Nizoral);

  • carbamazepine (Tegretol);

  • phenytoin (Dilantin); or

  • rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin).

You may not be able to take nifedipine, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with nifedipine or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

  • Your pharmacist has additional information about nifedipine written for health professionals that you may read.

What does my medication look like?

Nifedipine is available with a prescription generically and under the brand names Adalat, Adalat CC, Procardia, and Procardia XL. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Adalat 10 mg--orange, soft-gelatin capsules

  • Adalat 20 m --orange/light brown, soft-gelatin capsules

  • Adalat CC 30 mg--round, pink, film-coated tablets

  • Adalat CC 60 mg--round, salmon-colored, film-coated tablets

  • Adalat CC 90 mg--round, dark-red, film-coated tablets

  • Procardia 10 mg--orange, soft-gelatin capsules

  • Procardia 20 mg--orange/light-brown, soft-gelatin capsules

  • Procardia XL 30 mg--round, rose-pink, biconvex, film-coated tablets

  • Procardia XL 60 mg--round, rose-pink, biconvex, film-coated tablets

  • Procardia XL 90 mg--round, rose-pink, biconvex, film-coated tablets

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