Drug NameAceon (Perindopril) Drug UsesAceon is used to treat high blood pressure (hypertension) and to prevent heart attack in people with coronary artery disease. How to useThe usual starting dosage is 4 milligrams daily, taken as a single dose or divided into two smaller doses. Your doctor may increase the dosage until your blood pressure is under control, up to a maximum of 16 milligrams per day. Drug Class and MechanismAceon is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking ACE, an enzyme involved in narrowing blood vessels and causing sodium and fluid retention by the kidneys.
This causes blood vessels to relax, allowing blood to flow more freely and at a lower pressure, and increasing the heart's ability to pump blood in some types of heart failure. Missed DoseTake the missed dose as soon as you remember. However, if it is too late or almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Storage Store at room temperature, protected from moisture. Possible Side EffectsIf any side effects develop, they are usually mild and are likely to disappear as therapy continues. However, if any do appear, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Aceon. More common side effects may include:
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cough, dizziness, headache, leg pain, light-headedness, nasal inflammation, sore throat, upper respiratory infection, weakness.
More InformationAceon can cause injury or death to the developing baby when used during the last 6 months of pregnancy. Aceon should be stopped as soon as you know that you're pregnant; contact your doctor immediately. Warnings/PrecautionsAceon can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of perindopril.
Do not use salt substitutes or potassium supplements while taking perindopril, unless your doctor has told you to.
A persistent, unproductive cough may occur. Tell your doctor if this occurs. Recovery is rapid when the medicine is stopped.
Aceon may lower your resistance to infection. Prevent infection by avoiding contact with people with colds or other infections. Do not touch you eyes or the inside of your nose unless you have thoroughly washed your hands first.
What is perindopril?
Perindopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.
Perindopril is used to treat high blood pressure (hypertension) and to prevent heart attack in people with coronary artery disease.
Perindopril may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about perindopril?
Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Perindopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of perindopril. Do not use salt substitutes or potassium supplements while taking perindopril, unless your doctor has told you to.
Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking perindopril. Drink plenty of water each day while you are taking this medication.
What should I discuss with my healthcare provider before taking perindopril?
Do not use this medication if you are allergic to perindopril or to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).
Before using perindopril, tell your doctor if you are allergic to any drugs, or if you have:
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kidney disease (or if you are on dialysis);
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liver disease;
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heart disease or congestive heart failure;
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diabetes; or
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a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.
If you have any of these conditions, you may not be able to use perindopril, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Perindopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. It is not known whether perindopril passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take perindopril?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Take each dose with a full glass of water.
Perindopril can be taken with or without food.
Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking perindopril. Drink plenty of water each day while you are taking this medication.
To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
If you need to have any type of surgery, tell the surgeon ahead of time that you are taking perindopril. You may need to stop using the medicine for a short time.
If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.
Store perindopril at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a perindopril overdose may include feeling extremely dizzy or light-headed, or fainting.
What should I avoid while taking perindopril?
Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of perindopril. Do not use salt substitutes or potassium supplements while taking perindopril, unless your doctor has told you to.
Perindopril side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
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feeling light-headed, fainting;
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urinating more or less than usual, or not at all;
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fever, chills, body aches, flu symptoms;
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pale skin, easy bruising or bleeding;
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tired feeling, muscle weakness, and pounding or uneven heartbeats;
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swelling, rapid weight gain;
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chest pain; or
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jaundice (yellowing of the skin or eyes).
Less serious side effects may be more likely to occur, such as:
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cough, stuffy nose;
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muscle or joint pain;
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dizziness, drowsiness, headache;
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sleep problems (insomnia);
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diarrhea, upset stomach; or
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mild skin itching or rash.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect perindopril?
Before taking perindopril, tell your doctor if you are taking any of the following drugs:
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lithium (Lithobid, Eskalith);
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a potassium supplement such as K-Dur, Klor-Con;
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salt substitutes that contain potassium; or
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a diuretic (water pill).
If you are using any of these drugs, you may not be able to use perindopril or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect perindopril. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist has information about perindopril written for health professionals that you may read.
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