Drug NameAccupril (Quinapril) Drug UsesAccupril is used for lowering high blood pressure and managing heart failure. How to useUse Accupril as directed by your doctor.
- Take Accupril by mouth on an empty stomach at least 1 hour before or 2 hours after eating, or with a light meal. High-fat meals, however, may decrease the absorption of the medicine into your bloodstream.
- If you are taking a tetracyclines (eg, doxycycline) or fluoroquinolones (e.g., ciprofloxacin), take it at least 3 hours apart from Accupril . This product contains magnesium, which can interfere with absorption of these antibiotics.
Ask your health care provider any questions you may have about how to use Accupril. Drug Class and MechanismAccupril is an angiotensin-converting enzyme (ACE) inhibitor. ACE is involved in certain chemical reactions that constrict (narrow) blood vessels and cause sodium and fluid retention by the kidney. Missed DoseIf a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. If more than one dose is missed, contact your health care provider or pharmacist. Storage Store Accupril at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Protect from moisture, heat, and light. Do not store in the bathroom. Keep Accupril out of the reach of children and away from pets. Possible Side EffectsCheck with your doctor if any of these most common side effects persist or become bothersome:
- chest pain; coughing; diarrhea; difficulty breathing; dizziness; headache; lightheadedness; nausea; persistent, dry cough; tiredness; vomiting.
Seek medical attention right away if any of these severe side effects occur:
- severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; difficulty swallowing or breathing; fainting; hoarseness; infection (sore throat, fever); irregular or slow heartbeat; shortness of breath; unusual stomach pain; yellowing of the skin or eyes.
More InformationAccupril is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor. Warnings/PrecautionsDo not use Accupril if:
- you are allergic to any ingredient in Accupril;
- you you are in the second or third trimester of pregnancy;
- you have a history of angioedema (swelling of the face, lips, throat, or tongue) caused by treatment with an ACE inhibitor.
Contact your doctor or health care provider right away if any of these apply to you.
Important :
- Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Accupril has magnesium in it. Before you start any new medicine, check the label to see if it has magnesium in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- Accupril may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Accupril . Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Check with your doctor before you use a salt substitute or a product that has potassium in it.
- Dehydration, excessive sweating, vomiting, or diarrhea may lead to a fall in blood pressure. Contact your health care provider at once if any of these occur.
- Accupril may not work as well in black patients. They may also be at greater risk of side effects. Contact your doctor if your symptoms do not improve or if they become worse.
- Tell your doctor or dentist that you take Accupril before you receive any medical or dental care, emergency care, or surgery.
- Lab tests, including electrolyte levels, may be performed while you use Accupril . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Accupril should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
- Pregnancy and breast-feeding: Do not use Accupril if you are pregnant. It has been shown to cause death to the fetus and newborn. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Accupril is found in the breast milk. If you are or will be breast-feeding while you use Accupril, check with your doctor. Discuss any possible risks to your baby.
What is quinapril?
Quinapril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.
Quinapril is used to treat high blood pressure (hypertension) and heart failure.
Quinapril may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about quinapril?
Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Quinapril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of quinapril. Do not use salt substitutes or potassium supplements while taking quinapril, unless your doctor has told you to.
Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking quinapril. Drink plenty of water each day while you are taking this medication.
What should I discuss with my healthcare provider before taking quinapril?
Do not use this medication if you are allergic to quinapril or to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), ramipril (Altace), or trandolapril (Mavik).
Before using quinapril, tell your doctor if you are allergic to any drugs, or if you have:
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kidney disease (or if you are on dialysis);
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liver disease;
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heart disease or congestive heart failure;
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diabetes; or
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a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.
If you have any of these conditions, you may not be able to use quinapril, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Quinapril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Quinapril can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take quinapril?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results from this medication.
Take each dose with a full glass of water.
Quinapril can be taken with or without food.
Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking quinapril. Drink plenty of water each day while you are taking this medication.
To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.
If you need to have any type of surgery, tell the surgeon ahead of time that you are taking quinapril. You may need to stop using the medicine for a short time.
If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.
Store quinapril at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a quinapril overdose may include feeling extremely dizzy or light-headed, or fainting.
What should I avoid while taking quinapril?
Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of quinapril. Do not use salt substitutes or potassium supplements while taking quinapril, unless your doctor has told you to.
Quinapril side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
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feeling light-headed, fainting;
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urinating more or less than usual, or not at all;
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fever, chills, body aches, flu symptoms;
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pale skin, easy bruising or bleeding;
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severe blistering, peeling, and red skin rash;
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tired feeling, muscle weakness, and pounding or uneven heartbeats;
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chest pain;
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swelling, rapid weight gain; or
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jaundice (yellowing of the skin or eyes).
Less serious side effects may be more likely to occur, such as:
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cough;
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muscle pain;
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dizziness, drowsiness, headache;
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nausea, vomiting, diarrhea; or
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mild skin itching or rash.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect quinapril?
Before taking quinapril, tell your doctor if you are taking any of the following drugs:
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lithium (Lithobid, Eskalith);
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tetracycline (Brodspec, Panamycin, Sumycin, Tetracap);
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a potassium supplement such as K-Dur, Klor-Con;
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salt substitutes that contain potassium; or
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a diuretic (water pill).
If you are using any of these drugs, you may not be able to use quinapril or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect quinapril. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
- Your pharmacist has information about quinapril written for health professionals that you may read.
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